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Aubrey Stoch Selected Research

N- (3- (4- chlorophenyl)- 2- (3- cyanophenyl)- 1- methylpropyl)- 2- methyl- 2- ((5- (trifluoromethyl)pyridin- 2- yl)oxy)propanamide

10/2010Metabolism and excretion of [14C]taranabant, a cannabinoid-1 inverse agonist, in humans.
6/2008Multiple-dose pharmacokinetics, pharmacodynamics, and safety of taranabant, a novel selective cannabinoid-1 receptor inverse agonist, in healthy male volunteers.
4/2008Safety, tolerability, pharmacokinetics, and pharmacodynamic properties of taranabant, a novel selective cannabinoid-1 receptor inverse agonist, for the treatment of obesity: results from a double-blind, placebo-controlled, single oral dose study in healthy volunteers.
1/2008The acyclic CB1R inverse agonist taranabant mediates weight loss by increasing energy expenditure and decreasing caloric intake.

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Aubrey Stoch Research Topics

Disease

4Obesity
10/2010 - 01/2008
2Chronic Cough
09/2022 - 01/2022
2Type 2 Diabetes Mellitus (MODY)
11/2014 - 12/2013
1Neoplasms (Cancer)
01/2021
1Non-alcoholic Fatty Liver Disease
01/2018
1Metabolic Diseases (Metabolic Disease)
01/2018
1Abdominal Pain (Pain, Abdominal)
04/2008
1Hiccup (Hiccups)
04/2008
1Nausea
04/2008
1Headache (Headaches)
04/2008
1Vomiting
04/2008
1Dizziness (Lightheadedness)
04/2008
1Weight Loss (Weight Reduction)
01/2008

Drug/Important Bio-Agent (IBA)

4N- (3- (4- chlorophenyl)- 2- (3- cyanophenyl)- 1- methylpropyl)- 2- methyl- 2- ((5- (trifluoromethyl)pyridin- 2- yl)oxy)propanamideIBA
10/2010 - 01/2008
3CannabinoidsIBA
10/2010 - 01/2008
2GefapixantIBA
09/2022 - 01/2022
1Monoclonal AntibodiesIBA
01/2021
1Biological ProductsIBA
01/2021
1FructoseIBA
01/2018
1Indicators and Reagents (Reagents)IBA
01/2018
1Glucagon Receptors (Glucagon Receptor)IBA
11/2014
1VildagliptinIBA
12/2013
1Sitagliptin Phosphate (Januvia)FDA Link
12/2013
1saxagliptinFDA Link
12/2013
1Pharmaceutical PreparationsIBA
04/2008

Therapy/Procedure

1Therapeutics
01/2008